SCOPe 2.05: Domain d1ptmb_: 1ptm B:

Lineage for d1ptmb_ (1ptm B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.3: PdxA-like [102656] (2 proteins)
   Pfam PF04166; contains extra beta-alpha unit between strands 2 and 3; closer relationships to the PlsX-like and phosphotransacetylase families

6. Protein 4-hydroxythreonine-4-phosphate dehydrogenase PdxA [102657] (2 species)
   pyridoxal phosphate biosynthetic protein

7. Species Escherichia coli [TaxId:562] [102658] (3 PDB entries)

8. Domain d1ptmb_: 1ptm B: [95105]
   complexed with po4, zn

Details for d1ptmb_

PDB Entry: 1ptm, 1.96 Å

PDB Description: crystal structure of e.coli pdxa

PDB Compounds: (B:) 4-hydroxythreonine-4-phosphate dehydrogenase

SCOPe Domain Sequences for d1ptmb_:

Sequence; same for both SEQRES and ATOM records:

>d1ptmb_ c.77.1.3 (B:) 4-hydroxythreonine-4-phosphate dehydrogenase PdxA {Escherichia coli [TaxId: 562]}
vktqrvvitpgepagigpdlvvqlaqrewpvelvvcadatlltnraamlglpltlrpysp
nspaqpqtagtltllpvalrapvtagqlavenghyvvetlaracdgclngefaalitgpv
hkgvindagipftghteffeersqakkvvmmlateelrvalatthlplrdiadaitpall
heviailhhdlrtkfgiaeprilvcglnphagegghmgteeidtiipvlnelraqgmkln
gplpadtlfqpkyldnadavlamyhdqglpvlkyqgfgrgvnitlglpfirtsvdhgtal
elagrgkadvgsfitalnlaikmivntq

Timeline for d1ptmb_:

• d1ptmb_ first appeared in SCOP 1.67
  
• d1ptmb_ appears in SCOPe 2.04
  
• d1ptmb_ appears in SCOPe 2.06
  
• d1ptmb_ appears in the current release, SCOPe 2.08