SCOPe 2.06: Domain d1pl8c1: 1pl8 C:1-145,C:317-356

Lineage for d1pl8c1 (1pl8 C:1-145,C:317-356)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.35: GroES-like [50128] (2 superfamilies)
   contains barrel, partly opened; n*=4, S*=8; meander

4. Superfamily b.35.1: GroES-like [50129] (3 families)

5. Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain [50136] (15 proteins)
   C-terminal domain is alpha/beta (classical Rossmann-fold)

6. Protein Ketose reductase (sorbitol dehydrogenase) [50145] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101710] (3 PDB entries)

8. Domain d1pl8c1: 1pl8 C:1-145,C:317-356 [94882]
   Other proteins in same PDB: d1pl8a2, d1pl8b2, d1pl8c2, d1pl8d2
   complexed with nad, zn

Details for d1pl8c1

PDB Entry: 1pl8, 1.9 Å

PDB Description: human SDH/NAD+ complex

PDB Compounds: (C:) human sorbitol dehydrogenase

SCOPe Domain Sequences for d1pl8c1:

Sequence; same for both SEQRES and ATOM records:

>d1pl8c1 b.35.1.2 (C:1-145,C:317-356) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
aaaakpnnlslvvhgpgdlrlenypipepgpnevllrmhsvgicgsdvhyweygrignfi
vkkpmvlgheasgtvekvgssvkhlkpgdrvaiepgaprendefckmgrynlspsiffca
tppddgnlcrfykhnaafcyklpdnXvkplvthrfplekaleafetfkkglglkimlkcd
psdqnp

Timeline for d1pl8c1:

• d1pl8c1 first appeared in SCOP 1.67
  
• d1pl8c1 appears in SCOPe 2.05
  
• d1pl8c1 appears in SCOPe 2.07
  
• d1pl8c1 appears in the current release, SCOPe 2.08