Lineage for d1pj2d2 (1pj2 D:3021-3279)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2466799Fold c.58: Aminoacid dehydrogenase-like, N-terminal domain [53222] (1 superfamily)
    core: 3 layers: a/b/a; parallel beta-sheet of 4 strands; 2134
  4. 2466800Superfamily c.58.1: Aminoacid dehydrogenase-like, N-terminal domain [53223] (6 families) (S)
  5. 2466982Family c.58.1.3: Malic enzyme N-domain [53240] (2 proteins)
    Pfam PF00390; decorated with additional structures; includes N-terminal additional subdomains and extra N-terminal strand
  6. 2466989Protein Mitochondrial NAD(P)-dependent malic enzyme [53241] (3 species)
  7. 2467007Species Human (Homo sapiens) [TaxId:9606] [53242] (10 PDB entries)
  8. 2467023Domain d1pj2d2: 1pj2 D:3021-3279 [94725]
    Other proteins in same PDB: d1pj2a1, d1pj2b1, d1pj2c1, d1pj2d1
    complexed with fum, mlt, mn, nai

Details for d1pj2d2

PDB Entry: 1pj2 (more details), 2.3 Å

PDB Description: crystal structure of human mitochondrial nad(p)+-dependent malic enzyme in a pentary complex with natural substrate malate, cofactor nadh, mn++, and allosteric activator fumarate
PDB Compounds: (D:) NAD-dependent malic enzyme, mitochondrial

SCOPe Domain Sequences for d1pj2d2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1pj2d2 c.58.1.3 (D:3021-3279) Mitochondrial NAD(P)-dependent malic enzyme {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1pj2d2:

Click to download the PDB-style file with coordinates for d1pj2d2.
(The format of our PDB-style files is described here.)

Timeline for d1pj2d2: