Lineage for d1pfba_ (1pfb A:)

  1. Root: SCOP 1.67
  2. 362614Class b: All beta proteins [48724] (141 folds)
  3. 372425Fold b.34: SH3-like barrel [50036] (15 superfamilies)
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. 373032Superfamily b.34.13: Chromo domain-like [54160] (2 families) (S)
    SH3-like barrel is capped by a C-terminal helix
  5. 373050Family b.34.13.2: Chromo domain [54165] (3 proteins)
    lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold
  6. 373068Protein Polycomb protein, Pc [101688] (1 species)
  7. 373069Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [101689] (2 PDB entries)
  8. 373070Domain d1pfba_: 1pfb A: [94655]
    complexed with histone H3 peptide containing trimethyllysine 27, chain B
    complexed with acy, bme, cl, m3l

Details for d1pfba_

PDB Entry: 1pfb (more details), 1.4 Å

PDB Description: structural basis for specific binding of polycomb chromodomain to histone h3 methylated at k27

SCOP Domain Sequences for d1pfba_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1pfba_ b.34.13.2 (A:) Polycomb protein, Pc {Fruit fly (Drosophila melanogaster)}
dlvyaaekiiqkrvkkgvveyrvkwkgwnqryntwepevnildrrlidiyeqtnk

SCOP Domain Coordinates for d1pfba_:

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Timeline for d1pfba_: