SCOPe 2.01: Domain d1pcwb_: 1pcw B:

Lineage for d1pcwb_ (1pcw B:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.4: Class I DAHP synthetase [51599] (3 proteins)

6. Protein 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) [51602] (4 species)

7. Species Aquifex aeolicus [TaxId:63363] [63922] (32 PDB entries)

8. Domain d1pcwb_: 1pcw B: [94496]
   complexed with cd, h4p

Details for d1pcwb_

PDB Entry: 1pcw, 1.85 Å

PDB Description: Aquifex aeolicus KDO8PS in complex with cadmium and APP, a bisubstrate inhibitor

PDB Compounds: (B:) 2-dehydro-3-deoxyphosphooctonate aldolase

SCOPe Domain Sequences for d1pcwb_:

Sequence, based on SEQRES records:

>d1pcwb_ c.1.10.4 (B:) 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) {Aquifex aeolicus [TaxId: 63363]}
kflviagpcaieseelllkvgeeikrlsekfkevefvfkssfdkanrssihsfrghgley
gvkalrkvkeefglkittdiheswqaepvaevadiiqipaflcrqtdlllaaaktgravn
vkkgqflapwdtknvveklkfggakeiyltergttfgynnlvvdfrslpimkqwakviyd
athsvqlpgglgdksggmrefifpliraavavgcdgvfmethpepekalsdastqlplsq
legiieaileirevaskyyeti

Sequence, based on observed residues (ATOM records):

>d1pcwb_ c.1.10.4 (B:) 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) {Aquifex aeolicus [TaxId: 63363]}
kflviagpcaieseelllkvgeeikrlsekfkevefvfkssfdkanrssihsfrghgley
gvkalrkvkeefglkittdiheswqaepvaevadiiqipaflcrqtdlllaaaktgravn
vkkgqflapwdtknvveklkfggakeiyltergttfgynnlvvdfrslpimkqwakviyd
athsvqlpgmrefifpliraavavgcdgvfmethpepekalsdastqlplsqlegiieai
leirevaskyyeti

Timeline for d1pcwb_:

• d1pcwb_ first appeared in SCOP 1.67
  
• d1pcwb_ appears in SCOP 1.75
  
• d1pcwb_ appears in SCOPe 2.02
  
• d1pcwb_ appears in the current release, SCOPe 2.08