SCOPe 2.05: Domain d1pcgb_: 1pcg B:

Lineage for d1pcgb_ (1pcg B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (61 PDB entries)
   Uniprot P03372 307-551

8. Domain d1pcgb_: 1pcg B: [94433]
   complexed with est

Details for d1pcgb_

PDB Entry: 1pcg, 2.7 Å

PDB Description: helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d1pcgb_:

Sequence, based on SEQRES records:

>d1pcgb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
nslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakr
vpgfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmve
ifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkit
dtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplydlllem
ldah

Sequence, based on observed residues (ATOM records):

>d1pcgb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
nslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakr
vpgfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmve
ifdmllatssrfrmmnlqgeefvclksiillnsgvytflstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplydllleml
dah

Timeline for d1pcgb_:

• d1pcgb_ first appeared in SCOP 1.67
  
• d1pcgb_ appears in SCOPe 2.04
  
• d1pcgb_ appears in SCOPe 2.06
  
• d1pcgb_ appears in the current release, SCOPe 2.08