SCOPe 2.08: Domain d1p9oa_: 1p9o A:

Lineage for d1p9oa_ (1p9o A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.3: CoaB-like [102645] (2 families)
   combination of the Rossmann-like and Ribokinase-like topologies; mixed beta-sheet of 8 strands, order 32145678, strand 7 is antiparallel to the rest

5. Family c.72.3.1: CoaB-like [102646] (3 proteins)
   Pfam PF04127

6. Protein Phosphopantothenoylcysteine synthetase [102647] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102648] (1 PDB entry)

8. Domain d1p9oa_: 1p9o A: [94397]
   complexed with so4

Details for d1p9oa_

PDB Entry: 1p9o, 2.3 Å

PDB Description: Crystal Structure of Phosphopantothenoylcysteine Synthetase

PDB Compounds: (A:) Phosphopantothenoylcysteine synthetase

SCOPe Domain Sequences for d1p9oa_:

Sequence, based on SEQRES records:

>d1p9oa_ c.72.3.1 (A:) Phosphopantothenoylcysteine synthetase {Human (Homo sapiens) [TaxId: 9606]}
rwaevmarfaarlgaqgrrvvlvtsggtkvplearpvrfldnfssgrrgatsaeaflaag
ygvlflyrarsafpyahrfppqtwlsalrpsgpalsgllsleaeenalpgfaealrsyqe
aaaagtflvvefttladylhllqaaaqalnplgpsamfylaaavsdfyvpvsempehkie
ssggplqitmkmvpkllsplvkdwapkafiisfkletdpaivinrarkaleiyqhqvvva
nilesrqsfvlivtkdsetklllseeeiekgveieekivdnlqsrhtafi

Sequence, based on observed residues (ATOM records):

>d1p9oa_ c.72.3.1 (A:) Phosphopantothenoylcysteine synthetase {Human (Homo sapiens) [TaxId: 9606]}
rwaevmarfaarlgaqgrrvvlvtsggtkvplearpvrfldnfssgrrgatsaeaflaag
ygvlflyrarsafpyahrfppqtwlsalrpsgplsgllsleaeenalpgfaealrsyqea
aaagtflvvefttladylhllqaaaqalnplgpsamfylaaavsdfyvpplqitmkmvpk
llsplvkdwapkafiisfkletdpaivinrarkaleiyqhqvvvanifvlivtkdsetkl
llseeeiekgveieekivdnlqsrhtafi

Timeline for d1p9oa_:

• d1p9oa_ first appeared in SCOP 1.67
  
• d1p9oa_ appears in SCOPe 2.07