Lineage for d1p4rb1 (1p4r B:5-200)

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 579759Fold c.24: Methylglyoxal synthase-like [52334] (1 superfamily)
    3 layers, a/b/a; parallel beta-sheet of 5 strands, order 32145
  4. 579760Superfamily c.24.1: Methylglyoxal synthase-like [52335] (3 families) (S)
    contains a common phosphate-binding site
  5. 579837Family c.24.1.3: Inosicase [63971] (1 protein)
  6. 579838Protein IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC [63972] (2 species)
  7. 579848Species Human (Homo sapiens) [TaxId:9606] [102255] (3 PDB entries)
  8. 579854Domain d1p4rb1: 1p4r B:5-200 [94115]
    Other proteins in same PDB: d1p4ra2, d1p4rb2
    complexed with 354, amz, k, xmp

Details for d1p4rb1

PDB Entry: 1p4r (more details), 2.55 Å

PDB Description: Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD

SCOP Domain Sequences for d1p4rb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1p4rb1 c.24.1.3 (B:5-200) IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC {Human (Homo sapiens)}

SCOP Domain Coordinates for d1p4rb1:

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Timeline for d1p4rb1:

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