SCOP 1.67: Domain d1p49a_: 1p49 A:

Lineage for d1p49a_ (1p49 A:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.76: Alkaline phosphatase-like [53648] (1 superfamily)
   core:3 layers: a/b/a; mixed beta-sheet of 8 strands, order 43516728, strand 7 is antiparallel to the rest

4. Superfamily c.76.1: Alkaline phosphatase-like [53649] (4 families)

5. Family c.76.1.2: Arylsulfatase [53653] (3 proteins)
   includes additional C-terminal alpha+beta (sub)domain

6. Protein Steryl-sulfatase [102649] (1 species)
   contains membrane-anchoring alpha-hairpin insertion

7. Species Human (Homo sapiens) [TaxId:9606] [102650] (1 PDB entry)
   placental estrone/DHEA sulfatase

8. Domain d1p49a_: 1p49 A: [94089]
   complexed with als, bog, ca, nag, po4

Details for d1p49a_

PDB Entry: 1p49, 2.6 Å

PDB Description: structure of human placental estrone/dhea sulfatase

SCOP Domain Sequences for d1p49a_:

Sequence, based on SEQRES records:

>d1p49a_ c.76.1.2 (A:) Steryl-sulfatase {Human (Homo sapiens)}
aasrpniilvmaddlgigdpgcygnktirtpnidrlasggvkltqhlaasplctpsraaf
mtgrypvrsgmaswsrtgvflftassgglptdeitfakllkdqgystaligkwhlgmsch
sktdfchhplhhgfnyfygisltnlrdckpgegsvfttgfkrlvflplqivgvtlltlaa
lnclgllhvplgvffsllflaaliltlflgflhyfrplncfmmrnyeiiqqpmsydnltq
rltveaaqfiqrntetpfllvlsylhvhtalfsskdfagksqhgvygdaveemdwsvgqi
lnlldelrlandtliyftsdqgahveevsskgeihggsngiykggkannweggirvpgil
rwprviqagqkideptsnmdifptvaklagaplpedriidgrdlmpllegksqrsdhefl
fhycnaylnavrwhpqnstsiwkaffftpnfnpvgsngcfathvcfcfgsyvthhdppll
fdiskdprernpltpaseprfyeilkvmqeaadrhtqtlpevpdqfswnnflwkpwlqlc
cpstglscqcdre

Sequence, based on observed residues (ATOM records):

>d1p49a_ c.76.1.2 (A:) Steryl-sulfatase {Human (Homo sapiens)}
aasrpniilvmaddlgigdpgcygnktirtpnidrlasggvkltqhlaasplctpsraaf
mtgrypvrsgmaswsrtgvflftassgglptdeitfakllkdqgystaligkwhlgmsch
sktdfchhplhhgfnyfygisltnlrdckpgegsvfttgfkrlvflplqivgvtlltlaa
lnclgllhvplgvffsllflaaliltlflgflhyfrplncfmmrnyeiiqqpmsydnltq
rltveaaqfiqrntetpfllvlsylhvhtalfsskdfagksqhgvygdaveemdwsvgqi
lnlldelrlandtliyftsdqgahveevsskgeihggsngiykggkannweggirvpgil
rwprviqagqkideptsnmdifptvaklagaplpedriidgrdlmpllegksqrsdhefl
fhycnaylnavrwhpqnstsiwkaffftpnfnpvcfathvcfcfgsyvthhdppllfdis
kdprernpltpaseprfyeilkvmqeaadrhtqtlpevpdqfswnnflwkpwlqlccpst
glscqcdre

Timeline for d1p49a_:

• d1p49a_ is new in SCOP 1.67
  
• d1p49a_ appears in SCOP 1.69
  
• d1p49a_ appears in the current release, SCOPe 2.08