SCOP 1.67: Domain d1p0ha_: 1p0h A:

Lineage for d1p0ha_ (1p0h A:)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.108: Acyl-CoA N-acyltransferases (Nat) [55728] (1 superfamily)
   3 layers: a/b/a; contains mixed beta-sheet

4. Superfamily d.108.1: Acyl-CoA N-acyltransferases (Nat) [55729] (5 families)

5. Family d.108.1.1: N-acetyl transferase, NAT [55730] (18 proteins)

6. Protein Mycothiol synthase MshD [103175] (1 species)
   duplication: consists of two NAT domains swapped with the C-terminal strands with both domains binding acetyl-CoA; structural link with the other families

7. Species Mycobacterium tuberculosis [TaxId:1773] [103176] (2 PDB entries)
   Rv0819

8. Domain d1p0ha_: 1p0h A: [93866]
   complexed with aco, coa

Details for d1p0ha_

PDB Entry: 1p0h, 1.6 Å

PDB Description: Crystal Structure of Rv0819 from Mycobacterium Tuberculosis MshD-Mycothiol Synthase Coenzyme A Complex

SCOP Domain Sequences for d1p0ha_:

Sequence, based on SEQRES records:

>d1p0ha_ d.108.1.1 (A:) Mycothiol synthase MshD {Mycobacterium tuberculosis}
aldwrsaltadeqrsvralvtattavdgvapvgeqvlrelgqqrtehllvagsrpggpii
gylnlspprgaggamaelvvhpqsrrrgigtamaraalaktagrnqfwahgtldparata
salglvgvreliqmrrplrdipeptipdgvvirtyagtsddaellrvnnaafaghpeqgg
wtavqlaerrgeawfdpdglilafgdsprerpgrllgfhwtkvhpdhpglgevyvlgvdp
aaqrrglgqmltsigivslarrlggrktldpavepavllyvesdnvaavrtyqslgftty
svdtayal

Sequence, based on observed residues (ATOM records):

>d1p0ha_ d.108.1.1 (A:) Mycothiol synthase MshD {Mycobacterium tuberculosis}
aldwrsaltadeqrsvralvtattavdgvapvgeqvlrelgqqrtehllvagsrpggpii
gylnlsppggamaelvvhpqsrrrgigtamaraalaktagrnqfwahgtldparatasal
glvgvreliqmrrplrdipeptipdgvvirtyagtsddaellrvnnaafaghpeqggwta
vqlaerrgeawfdpdglilafgdgrllgfhwtkvhpdhpglgevyvlgvdpaaqrrglgq
mltsigivslarrlvepavllyvesdnvaavrtyqslgfttysvdtayal

Timeline for d1p0ha_:

• d1p0ha_ is new in SCOP 1.67
  
• d1p0ha_ appears in SCOP 1.69
  
• d1p0ha_ appears in the current release, SCOPe 2.08