Lineage for d1osha_ (1osh A:)

  1. Root: SCOPe 2.05
  2. 1715731Class a: All alpha proteins [46456] (286 folds)
  3. 1747085Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 1747086Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 1747087Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)
  6. 1747158Protein Bile acid receptor FXR [101433] (2 species)
  7. 1747159Species Human (Homo sapiens) [TaxId:9606] [101434] (7 PDB entries)
  8. 1747160Domain d1osha_: 1osh A: [93496]
    complexed with fex

Details for d1osha_

PDB Entry: 1osh (more details), 1.8 Å

PDB Description: A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR
PDB Compounds: (A:) Bile acid receptor

SCOPe Domain Sequences for d1osha_:

Sequence, based on SEQRES records: (download)

>d1osha_ a.123.1.1 (A:) Bile acid receptor FXR {Human (Homo sapiens) [TaxId: 9606]}
shgeltpdqqtllhfimdsynkqrmpqeitnkilkeefsaeenfliltematnhvqvlve
ftkklpgfqtldhedqiallkgsaveamflrsaeifnkklpsghsdlleerirnsgisde
yitpmfsfyksigelkmtqeeyalltaivilspdrqyikdreaveklqeplldvlqklck
ihqpenpqhfacllgrltelrtfnhhhaemlmswrvndhkftpllceiwdv

Sequence, based on observed residues (ATOM records): (download)

>d1osha_ a.123.1.1 (A:) Bile acid receptor FXR {Human (Homo sapiens) [TaxId: 9606]}
shgeltpdqqtllhfimdsynkqrmpenfliltematnhvqvlveftkklpgfqtldhed
qiallkgsaveamflrsaeifnkklpsghsdlleerirnsgisdeyitpmfsfyksigel
kmtqeeyalltaivilspdrqyikdreaveklqeplldvlqklckihqpenpqhfacllg
rltelrtfnhhhaemlmswrvndhkftpllceiwdv

SCOPe Domain Coordinates for d1osha_:

Click to download the PDB-style file with coordinates for d1osha_.
(The format of our PDB-style files is described here.)

Timeline for d1osha_: