SCOPe 2.05: Domain d1opha_: 1oph A:

Lineage for d1opha_ (1oph A:)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (2 families)

5. Family e.1.1.1: Serpins [56575] (17 proteins)
   automatically mapped to Pfam PF00079

6. Protein Antitrypsin, alpha-1 [56582] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56583] (15 PDB entries)

8. Domain d1opha_: 1oph A: [93404]
   Other proteins in same PDB: d1ophb_
   complexed with trypsinogen

Details for d1opha_

PDB Entry: 1oph, 2.3 Å

PDB Description: non-covalent complex between alpha-1-pi-pittsburgh and s195a trypsin

PDB Compounds: (A:) Alpha-1-antitrypsin precursor

SCOPe Domain Sequences for d1opha_:

Sequence; same for both SEQRES and ATOM records:

>d1opha_ e.1.1.1 (A:) Antitrypsin, alpha-1 {Human (Homo sapiens) [TaxId: 9606]}
hptfnkitpnlaefafslyrqlahqsnstnilfspvsiaaafamlslgakgdthdeileg
lnfnlteipeaqihegfqellrtlnqpdsqlqlttgnglflseglklvdkfledvkklyh
seaftvnfgdteeakkqindyvekgtqgkivdlvkeldrdtvfalvnyiffkgkwerpfe
vkdteeedfhvdqvttvkvpmmkrlgmfniqhskklsswvllmkylgnataifflpdegk
lqhlenelthdiitkflenedrrsaslhlpklsitgtydlksvlgqlgitkvfsngadls
gvteeaplklskavhkavltidekgteaagamfleaiprsippevkfnkpfvfliieqnt
kaplfmgrvvnptqk

Timeline for d1opha_:

• d1opha_ first appeared in SCOP 1.67
  
• d1opha_ appears in SCOPe 2.04
  
• d1opha_ appears in SCOPe 2.06
  
• d1opha_ appears in the current release, SCOPe 2.08