SCOP 1.71: Domain d1ol6a_: 1ol6 A:

Lineage for d1ol6a_ (1ol6 A:)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (60 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
   OPK group; AIRK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [90039] (5 PDB entries)

8. Domain d1ol6a_: 1ol6 A: [93311]
   complexed with atp; mutant

Details for d1ol6a_

PDB Entry: 1ol6, 3 Å

PDB Description: Structure of unphosphorylated D274N mutant of Aurora-A

SCOP Domain Sequences for d1ol6a_:

Sequence, based on SEQRES records:

>d1ol6a_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens)}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqsh
lrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyc
hskrvihrdikpenlllgsagelkianfgwsvhapssrrttlcgtldylppemiegrmhd
ekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhn
psqrpmlrevlehpwitanss

Sequence, based on observed residues (ATOM records):

>d1ol6a_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens)}
waledfeigrplgkkfgnvylarekqskfilalkvlfkaqlekaehqlrreveiqshlrh
pnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsychsk
rvihrdikpenlllgsagelkianfgwsvhtldylppemiegmhdekvdlwslgvlcyef
lvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlrevlehpw
itanss

Timeline for d1ol6a_:

• d1ol6a_ first appeared in SCOP 1.67
  
• d1ol6a_ appears in SCOP 1.69
  
• d1ol6a_ appears in SCOP 1.73
  
• d1ol6a_ appears in the current release, SCOPe 2.07