SCOPe 2.08: Domain d1ol1a_: 1ol1 A:

Lineage for d1ol1a_ (1ol1 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
   Uniprot P24941

8. Domain d1ol1a_: 1ol1 A: [93298]
   Other proteins in same PDB: d1ol1b1, d1ol1b2, d1ol1d1, d1ol1d2
   complex with cyclin

Details for d1ol1a_

PDB Entry: 1ol1, 2.9 Å

PDB Description: cyclin a binding groove inhibitor h-cit-cit-leu-ile-(p-f-phe)-nh2

PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d1ol1a_:

Sequence; same for both SEQRES and ATOM records:

>d1ol1a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d1ol1a_:

• d1ol1a_ first appeared in SCOP 1.67
  
• d1ol1a_ appears in SCOPe 2.07