SCOPe 2.05: Domain d1o6rb2: 1o6r B:37-307

Lineage for d1o6rb2 (1o6r B:37-307)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families)

5. Family a.102.4.2: Terpene synthases [48243] (2 proteins)
   consists of two toroid domains: one of six and one of five hairpins

6. Protein Squalene-hopene cyclase [48244] (1 species)

7. Species Alicyclobacillus acidocaldarius [TaxId:405212] [48245] (16 PDB entries)

8. Domain d1o6rb2: 1o6r B:37-307 [92586]
   complexed with c8e, r19

Details for d1o6rb2

PDB Entry: 1o6r, 2.7 Å

PDB Description: structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme

PDB Compounds: (B:) squalene--hopene cyclase

SCOPe Domain Sequences for d1o6rb2:

Sequence; same for both SEQRES and ATOM records:

>d1o6rb2 a.102.4.2 (B:37-307) Squalene-hopene cyclase {Alicyclobacillus acidocaldarius [TaxId: 405212]}
lsnvtmeaeyvllchildrvdrdrmekirryllheqredgtwalypggppdldttieayv
alkyigmsrdeepmqkalrfiqsqggiessrvftrmwlalvgeypwekvpmvppeimflg
krmplniyefgswaratvvalsivmsrqpvfplperarvpelyetdvpprrrgakggggw
ifdaldralhgyqklsvhpfrraaeiraldwllerqagdgswggiqppwfyalialkild
mtqhpafikgweglelygveldyggwmfqas

Timeline for d1o6rb2:

• d1o6rb2 first appeared in SCOP 1.67
  
• d1o6rb2 appears in SCOPe 2.04
  
• d1o6rb2 appears in SCOPe 2.06
  
• d1o6rb2 appears in the current release, SCOPe 2.08