SCOP 1.67: Domain d1o66b_: 1o66 B:

Lineage for d1o66b_ (1o66 B:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (28 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (6 families)

5. Family c.1.12.8: Ketopantoate hydroxymethyltransferase PanB [89503] (1 protein)

6. Protein Ketopantoate hydroxymethyltransferase PanB [89504] (3 species)
   dodecameric enzyme; a C-terminal helix exchange is observed in the M. tuberculosis enzyme but not in the E. coli enzyme

7. Species Neisseria meningitidis [TaxId:487] [102100] (2 PDB entries)

8. Domain d1o66b_: 1o66 B: [92548]

Details for d1o66b_

PDB Entry: 1o66, 1.75 Å

PDB Description: crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase

SCOP Domain Sequences for d1o66b_:

Sequence, based on SEQRES records:

>d1o66b_ c.1.12.8 (B:) Ketopantoate hydroxymethyltransferase PanB {Neisseria meningitidis}
slitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpvs
lrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwma
etteflqmrgipvcahigltpqsvfafggykvqgrggkaqallndakahddagaavvlme
cvlaelakkvtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsvq
aavrayvaevkaktfpa

Sequence, based on observed residues (ATOM records):

>d1o66b_ c.1.12.8 (B:) Ketopantoate hydroxymethyltransferase PanB {Neisseria meningitidis}
slitvntlqkmkaagekiamltayessfaalmddagvemllvgdslgmavqgrkstlpvs
lrdmcyhtecvargaknamivsdlpfgayqqskeqafaaaaelmaagahmvkleggvwma
etteflqmrgipvcahigltpqsvfaggkaqallndakahddagaavvlmecvlaelakk
vtetvscptigigagadcdgqvlvmhdmlgifpgktakfvknfmqghdsvqaavrayvae
vkaktfpa

Timeline for d1o66b_:

• d1o66b_ is new in SCOP 1.67
  
• d1o66b_ appears in SCOP 1.69
  
• d1o66b_ appears in the current release, SCOPe 2.08, called d1o66b1