SCOPe 2.01: Domain d1nzkb_: 1nzk B:

Lineage for d1nzkb_ (1nzk B:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (10 proteins)

6. Protein Acidic FGF (FGF1) [50357] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50359] (31 PDB entries)
   Uniprot P05230 16-152 ! Uniprot P05230

8. Domain d1nzkb_: 1nzk B: [92379]
   complexed with fmt, so4; mutant

Details for d1nzkb_

PDB Entry: 1nzk, 1.95 Å

PDB Description: crystal structure of a multiple mutant (l44f, l73v, v109l, l111i, c117v) of human acidic fibroblast growth factor

PDB Compounds: (B:) acidic fibroblast growth factor

SCOPe Domain Sequences for d1nzkb_:

Sequence; same for both SEQRES and ATOM records:

>d1nzkb_ b.42.1.1 (B:) Acidic FGF (FGF1) {Human (Homo sapiens) [TaxId: 9606]}
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevyi
kstetgqylamdtdglvygsqtpneeclflerleenhyntyiskkhaeknwflgikkngs
vkrgprthygqkailflplpv

Timeline for d1nzkb_:

• d1nzkb_ first appeared in SCOP 1.67
  
• d1nzkb_ appears in SCOP 1.75
  
• d1nzkb_ appears in SCOPe 2.02
  
• d1nzkb_ appears in the current release, SCOPe 2.08