SCOP 1.67: Domain d1nxka_: 1nxk A:

Lineage for d1nxka_ (1nxk A:)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (47 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase activated protein kinase 2, mapkap2 [82789] (1 species)
   CaMK group; MAPKAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [82790] (3 PDB entries)

8. Domain d1nxka_: 1nxk A: [92302]

Details for d1nxka_

PDB Entry: 1nxk, 2.7 Å

PDB Description: Crystal structure of staurosporine bound to MAP KAP kinase 2

SCOP Domain Sequences for d1nxka_:

Sequence, based on SEQRES records:

>d1nxka_ d.144.1.7 (A:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens)}
qfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpka
rrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafter
easeimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnslt
tpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirm
gqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrv
lked

Sequence, based on observed residues (ATOM records):

>d1nxka_ d.144.1.7 (A:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens)}
qfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpka
rrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdraftereas
eimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevl
gpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgqyefpnpewsevs
eevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlked

Timeline for d1nxka_:

• d1nxka_ is new in SCOP 1.67
  
• d1nxka_ appears in SCOP 1.69
  
• d1nxka_ appears in the current release, SCOPe 2.08