Lineage for d1nl0l1 (1nl0 L:1-108)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2019185Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2019198Species Human (Homo sapiens), cluster 2 [TaxId:9606] [88536] (10 PDB entries)
  8. 2019202Domain d1nl0l1: 1nl0 L:1-108 [91947]
    Other proteins in same PDB: d1nl0g_, d1nl0h1, d1nl0h2, d1nl0l2
    part of Fab 10c12 against factor IX Gla domain
    complexed with ca, so4

Details for d1nl0l1

PDB Entry: 1nl0 (more details), 2.2 Å

PDB Description: Crystal structure of human factor IX Gla domain in complex of an inhibitory antibody, 10C12
PDB Compounds: (L:) anti-factor IX antibody, 10C12, chain L

SCOPe Domain Sequences for d1nl0l1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1nl0l1 b.1.1.1 (L:1-108) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 2 [TaxId: 9606]}

SCOPe Domain Coordinates for d1nl0l1:

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Timeline for d1nl0l1: