Lineage for d1nfbb3 (1nfb B:188-231)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 721299Fold d.37: CBS-domain [54630] (1 superfamily)
    core: beta-alpha-beta(4); 2 layers: alpha/beta
  4. 721300Superfamily d.37.1: CBS-domain [54631] (1 family) (S)
  5. 721301Family d.37.1.1: CBS-domain [54632] (10 proteins)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain
  6. 721353Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
  7. 721362Species Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)
  8. 721372Domain d1nfbb3: 1nfb B:188-231 [91863]
    Other proteins in same PDB: d1nfba1, d1nfbb1
    both CBS domains are partly disordered in both chains, A and B
    complexed with cpr, nad

Details for d1nfbb3

PDB Entry: 1nfb (more details), 2.9 Å

PDB Description: Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD
PDB Compounds: (B:) Inosine-5'-monophosphate dehydrogenase 2

SCOP Domain Sequences for d1nfbb3:

Sequence, based on SEQRES records: (download)

>d1nfbb3 d.37.1.1 (B:188-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type II [TaxId: 9606]}
apagitlkeaneilqrskkgklpivneddelvaiiartdlkknr

Sequence, based on observed residues (ATOM records): (download)

>d1nfbb3 d.37.1.1 (B:188-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type II [TaxId: 9606]}
apagitlkeaneilqrskkgklpivneddevaiianr

SCOP Domain Coordinates for d1nfbb3:

Click to download the PDB-style file with coordinates for d1nfbb3.
(The format of our PDB-style files is described here.)

Timeline for d1nfbb3: