SCOP 1.67: Domain d1nfbb3: 1nfb B:188-231

Lineage for d1nfbb3 (1nfb B:188-231)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.37: CBS-domain [54630] (1 superfamily)
   core: beta-alpha-beta(4); 2 layers: alpha/beta

4. Superfamily d.37.1: CBS-domain [54631] (1 family)

5. Family d.37.1.1: CBS-domain [54632] (4 proteins)
   pairs of CBS domains dimerize to form a stable globular domain

6. Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
   contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals

7. Species Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)

8. Domain d1nfbb3: 1nfb B:188-231 [91863]
   Other proteins in same PDB: d1nfba1, d1nfbb1
   both CBS domains are partly disordered in both chains, A and B
   complexed with cpr, nad

Details for d1nfbb3

PDB Entry: 1nfb, 2.9 Å

PDB Description: Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD

SCOP Domain Sequences for d1nfbb3:

Sequence, based on SEQRES records:

>d1nfbb3 d.37.1.1 (B:188-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type II}
apagitlkeaneilqrskkgklpivneddelvaiiartdlkknr

Sequence, based on observed residues (ATOM records):

>d1nfbb3 d.37.1.1 (B:188-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type II}
apagitlkeaneilqrskkgklpivneddevaiianr

Timeline for d1nfbb3:

• d1nfbb3 is new in SCOP 1.67
  
• d1nfbb3 appears in SCOP 1.69
  
• d1nfbb3 last appears in SCOP 1.73