Lineage for d1nf7a1 (1nf7 A:10-111,A:232-514)

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 968086Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 969415Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (1 family) (S)
    The phosphate moiety of substrate binds in the 'common' phosphate-binding site
  5. 969416Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein)
  6. 969417Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species)
  7. 969424Species Human (Homo sapiens), type II [TaxId:9606] [51418] (3 PDB entries)
  8. 969427Domain d1nf7a1: 1nf7 A:10-111,A:232-514 [91852]
    Other proteins in same PDB: d1nf7a4, d1nf7b4
    complexed with k, myd, rvp, unk

Details for d1nf7a1

PDB Entry: 1nf7 (more details), 2.65 Å

PDB Description: Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide
PDB Compounds: (A:) Inosine-5'-monophosphate dehydrogenase 2

SCOPe Domain Sequences for d1nf7a1:

Sequence, based on SEQRES records: (download)

>d1nf7a1 c.1.5.1 (A:10-111,A:232-514) Inosine monophosphate dehydrogenase (IMPDH) {Human (Homo sapiens), type II [TaxId: 9606]}
tsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvssp
mdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeXdyplaskdakkqllcga
aigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaa
qaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvpviadggiq
nvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldamdkhlssqn
ryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigaksltqvrammysgel
kfekrtssaqveggvhslhsyekrlf

Sequence, based on observed residues (ATOM records): (download)

>d1nf7a1 c.1.5.1 (A:10-111,A:232-514) Inosine monophosphate dehydrogenase (IMPDH) {Human (Homo sapiens), type II [TaxId: 9606]}
tsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvssp
mdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeXdyplaskdakkqllcga
aigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaa
qaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvpviadggiq
nvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldamikvaqgvs
gavqdkgsihkfvpyliagiqhscqdigaksltqvrammysgelkfekrtssaqveggvh
slhsyekrlf

SCOPe Domain Coordinates for d1nf7a1:

Click to download the PDB-style file with coordinates for d1nf7a1.
(The format of our PDB-style files is described here.)

Timeline for d1nf7a1:

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Domains from same chain:
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d1nf7a4