Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (1 family) The phosphate moiety of substrate binds in the 'common' phosphate-binding site |
Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein) |
Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species) |
Species Human (Homo sapiens), type II [TaxId:9606] [51418] (3 PDB entries) |
Domain d1nf7a1: 1nf7 A:10-111,A:232-514 [91852] Other proteins in same PDB: d1nf7a4, d1nf7b4 |
PDB Entry: 1nf7 (more details), 2.65 Å
SCOP Domain Sequences for d1nf7a1:
Sequence, based on SEQRES records: (download)
>d1nf7a1 c.1.5.1 (A:10-111,A:232-514) Inosine monophosphate dehydrogenase (IMPDH) {Human (Homo sapiens), type II [TaxId: 9606]} tsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvssp mdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeXdyplaskdakkqllcga aigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaa qaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvpviadggiq nvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldamdkhlssqn ryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigaksltqvrammysgel kfekrtssaqveggvhslhsyekrlf
>d1nf7a1 c.1.5.1 (A:10-111,A:232-514) Inosine monophosphate dehydrogenase (IMPDH) {Human (Homo sapiens), type II [TaxId: 9606]} tsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvssp mdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeXdyplaskdakkqllcga aigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaa qaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvpviadggiq nvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldamikvaqgvs gavqdkgsihkfvpyliagiqhscqdigaksltqvrammysgelkfekrtssaqveggvh slhsyekrlf
Timeline for d1nf7a1: