SCOPe 2.07: Domain d1nd7a1: 1nd7 A:545-917

Lineage for d1nd7a1 (1nd7 A:545-917)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.148: Hect, E3 ligase catalytic domain [56203] (1 superfamily)
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

4. Superfamily d.148.1: Hect, E3 ligase catalytic domain [56204] (2 families)
   automatically mapped to Pfam PF00632

5. Family d.148.1.1: Hect, E3 ligase catalytic domain [56205] (3 proteins)

6. Protein WW domain-containing protein 1, WWP1 [103308] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [103309] (1 PDB entry)

8. Domain d1nd7a1: 1nd7 A:545-917 [91817]
   Other proteins in same PDB: d1nd7a2

Details for d1nd7a1

PDB Entry: 1nd7, 2.1 Å

PDB Description: conformational flexibility underlies ubiquitin ligation mediated by the wwp1 hect domain e3 ligase

PDB Compounds: (A:) WW domain-containing protein 1

SCOPe Domain Sequences for d1nd7a1:

Sequence; same for both SEQRES and ATOM records:

>d1nd7a1 d.148.1.1 (A:545-917) WW domain-containing protein 1, WWP1 {Human (Homo sapiens) [TaxId: 9606]}
mgfrwklahfrylcqsnalpshvkinvsrqtlfedsfqqimalkpydlrrrlyvifrgee
gldygglarewffllshevlnpmyclfeyagknnyclqinpastinpdhlsyfcfigrfi
amalfhgkfidtgfslpfykrmlskkltikdlesidtefynsliwirdnnieecglemyf
svdmeilgkvtshdlklggsnilvteenkdeyiglmtewrfsrgvqeqtkafldgfnevv
plqwlqyfdekelevmlcgmqevdladwqrntvyrhytrnskqiiwfwqfvketdnevrm
rllqfvtgtcrlplggfaelmgsngpqkfciekvgkdtwlprshtcfnrldlppyksyeq
lkekllfaieete

Timeline for d1nd7a1:

• d1nd7a1 first appeared in SCOP 1.67, called d1nd7a_
  
• d1nd7a1 appears in SCOPe 2.06
  
• d1nd7a1 appears in the current release, SCOPe 2.08