Lineage for d1nc4b1 (1nc4 B:1-120)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2018105Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)
  8. 2018134Domain d1nc4b1: 1nc4 B:1-120 [91791]
    Other proteins in same PDB: d1nc4a1, d1nc4a2, d1nc4b2, d1nc4c1, d1nc4c2, d1nc4d2
    part of Fab 2d12.5
    complexed with cl, dof, gd3, nag

Details for d1nc4b1

PDB Entry: 1nc4 (more details), 2.25 Å

PDB Description: Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Gd-DOTA
PDB Compounds: (B:) monoclonal antibody 2d12.5, igg1 gamma heavy chain

SCOPe Domain Sequences for d1nc4b1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1nc4b1 b.1.1.1 (B:1-120) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}

SCOPe Domain Coordinates for d1nc4b1:

Click to download the PDB-style file with coordinates for d1nc4b1.
(The format of our PDB-style files is described here.)

Timeline for d1nc4b1: