Lineage for d1nc2a1 (1nc2 A:1-110)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2019185Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2019276Species Mouse (Mus musculus) [TaxId:10090] [88541] (35 PDB entries)
  8. 2019287Domain d1nc2a1: 1nc2 A:1-110 [91781]
    Other proteins in same PDB: d1nc2a2, d1nc2b1, d1nc2b2, d1nc2c2, d1nc2d1, d1nc2d2
    part of Fab 2d12.5
    complexed with cl, doe, nag, yt3

Details for d1nc2a1

PDB Entry: 1nc2 (more details), 2.1 Å

PDB Description: Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Y-DOTA
PDB Compounds: (A:) monoclonal antibody 2d12.5, lambda light chain

SCOPe Domain Sequences for d1nc2a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1nc2a1 b.1.1.1 (A:1-110) Immunoglobulin light chain lambda variable domain, VL-lambda {Mouse (Mus musculus) [TaxId: 10090]}

SCOPe Domain Coordinates for d1nc2a1:

Click to download the PDB-style file with coordinates for d1nc2a1.
(The format of our PDB-style files is described here.)

Timeline for d1nc2a1: