SCOPe 2.02: Domain d1n2ra1: 1n2r A:182-276

Lineage for d1n2ra1 (1n2r A:182-276)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Class I MHC, alpha-3 domain [88604] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88605] (157 PDB entries)
   Uniprot P30685 25-300 ! Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor ! Uniprot P30481 25-300 ! Uniprot P01892 25-298 ! Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor

8. Domain d1n2ra1: 1n2r A:182-276 [91561]
   Other proteins in same PDB: d1n2ra2, d1n2rb_
   complexed with acy

Details for d1n2ra1

PDB Entry: 1n2r, 1.7 Å

PDB Description: A natural selected dimorphism in HLA B*44 alters self, peptide reportoire and T cell recognition.

PDB Compounds: (A:) HLA class I histocompatibility antigen, BW-44(B-12) B*4403 alpha chain

SCOPe Domain Sequences for d1n2ra1:

Sequence; same for both SEQRES and ATOM records:

>d1n2ra1 b.1.1.2 (A:182-276) Class I MHC, alpha-3 domain {Human (Homo sapiens) [TaxId: 9606]}
adppkthvthhpisdhevtlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrtf
qkwaavvvpsgeeqrytchvqheglpkpltlrwep

Timeline for d1n2ra1:

• d1n2ra1 first appeared in SCOP 1.67
  
• d1n2ra1 appears in SCOPe 2.01
  
• d1n2ra1 appears in SCOPe 2.03
  
• d1n2ra1 appears in the current release, SCOPe 2.08