Lineage for d1mxhc_ (1mxh C:)

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1150729Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 1150730Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 1151047Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 1151374Protein Dihydropteridin reductase (pteridine reductase) [51769] (6 species)
  7. 1151438Species Trypanosoma cruzi [TaxId:5693] [102146] (2 PDB entries)
  8. 1151441Domain d1mxhc_: 1mxh C: [91492]
    complexed with dhf, nap

Details for d1mxhc_

PDB Entry: 1mxh (more details), 2.2 Å

PDB Description: crystal structure of substrate complex of putative pteridine reductase 2 (ptr2) from trypanosoma cruzi
PDB Compounds: (C:) pteridine reductase 2

SCOPe Domain Sequences for d1mxhc_:

Sequence, based on SEQRES records: (download)

>d1mxhc_ c.2.1.2 (C:) Dihydropteridin reductase (pteridine reductase) {Trypanosoma cruzi [TaxId: 5693]}
cpaavitggarrighsiavrlhqqgfrvvvhyrhsegaaqrlvaelnaaragsavlckgd
lslssslldccediidcsfrafgrcdvlvnnasayyptpllpgddtngaadakpidaqva
elfgsnavaplflirafarrqgeggawrsrnlsvvnlcdamtdlplpgfcvytmakhalg
gltraaalelaprhirvnavapglsllppampqetqeeyrrkvplgqseasaaqiadaia
flvskdagyitgttlkvdgglilara

Sequence, based on observed residues (ATOM records): (download)

>d1mxhc_ c.2.1.2 (C:) Dihydropteridin reductase (pteridine reductase) {Trypanosoma cruzi [TaxId: 5693]}
cpaavitggarrighsiavrlhqqgfrvvvhyrhsegaaqrlvaelnaaragsavlckgd
lslssslldccediidcsfrafgrcdvlvnnasayyptpllppidaqvaelfgsnavapl
flirafarrqsrnlsvvnlcdamtdlplpgfcvytmakhalggltraaalelaprhirvn
avapglsllppampqetqeeyrrkvplgqseasaaqiadaiaflvskdagyitgttlkvd
gglilara

SCOPe Domain Coordinates for d1mxhc_:

Click to download the PDB-style file with coordinates for d1mxhc_.
(The format of our PDB-style files is described here.)

Timeline for d1mxhc_: