SCOP 1.67: Domain d1mp8a_: 1mp8 A:

Lineage for d1mp8a_ (1mp8 A:)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (47 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Focal adhesion kinase 1 (fak) [103292] (1 species)
   PTK group; FAK subfamily; non-membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [103293] (1 PDB entry)

8. Domain d1mp8a_: 1mp8 A: [91384]
   complexed with adp

Details for d1mp8a_

PDB Entry: 1mp8, 1.6 Å

PDB Description: Crystal structure of Focal Adhesion Kinase (FAK)

SCOP Domain Sequences for d1mp8a_:

Sequence, based on SEQRES records:

>d1mp8a_ d.144.1.7 (A:) Focal adhesion kinase 1 (fak) {Human (Homo sapiens)}
dyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqeal
tmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlsta
layleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikwmapes
infrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlys
lmtkcwaydpsrrprftelkaqlstileeekaq

Sequence, based on observed residues (ATOM records):

>d1mp8a_ d.144.1.7 (A:) Focal adhesion kinase 1 (fak) {Human (Homo sapiens)}
dyeiqrerielgrcigegqfgdvhqgiymsppalavaiktcknctsdsvrekflqealtm
rqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstala
yleskrfvhrdiaarnvlvssndcvklgdlpikwmapesinfrrftsasdvwmfgvcmwe
ilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrprftelka
qlstileeekaq

Timeline for d1mp8a_:

• d1mp8a_ is new in SCOP 1.67
  
• d1mp8a_ appears in SCOP 1.69
  
• d1mp8a_ appears in the current release, SCOPe 2.08