SCOPe 2.02: Domain d1mjjl1: 1mjj L:1-107

Lineage for d1mjjl1 (1mjj L:1-107)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (15 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (127 PDB entries)
   Uniprot P01631 #KV2G_MOUSE Ig kappa chain V-II region 26-10; 79% sequence identity ! Uniprot P06310 # KV2F_HUMAN IG KAPPA CHAIN V-II REGION RPMI 6410 PRECURSOR ! Uniprot P03976 # KV2E_MOUSE (P03976) Ig kappa chain V-II region 17S29.1 ! Uniprot P01642 21-115 # ! KV2G_MOUSE IG KAPPA CHAIN V-II REGION 26-10

8. Domain d1mjjl1: 1mjj L:1-107 [91300]
   Other proteins in same PDB: d1mjja2, d1mjjb1, d1mjjb2, d1mjjh1, d1mjjh2, d1mjjl2
   part of the esterolytic Fab ms6-164
   complexed with hal, so4

Details for d1mjjl1

PDB Entry: 1mjj, 2.1 Å

PDB Description: high resolution crystal structure of the complex of the fab fragment of esterolytic antibody ms6-12 and a transition-state analog

PDB Compounds: (L:) immunoglobulin ms6-12

SCOPe Domain Sequences for d1mjjl1:

Sequence; same for both SEQRES and ATOM records:

>d1mjjl1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1 [TaxId: 10090]}
divmtqaapsvpvtpgesvsiscrssksllhsngntylywflqrpgqspqlliyrmsnla
sgvpdrfsgsgsgtaftlrisrveaedvgvyyclqhleypftfgagtklelk

Timeline for d1mjjl1:

• d1mjjl1 first appeared in SCOP 1.67
  
• d1mjjl1 appears in SCOPe 2.01
  
• d1mjjl1 appears in SCOPe 2.03
  
• d1mjjl1 appears in the current release, SCOPe 2.08