Lineage for d1lsoa2 (1lso A:12-203)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2429613Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (19 proteins)
    the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
    C-terminal domains also show some similarity
  6. 2429761Protein Short chain L-3-hydroxyacyl CoA dehydrogenase [51874] (2 species)
  7. 2429762Species Human (Homo sapiens) [TaxId:9606] [51875] (11 PDB entries)
  8. 2429783Domain d1lsoa2: 1lso A:12-203 [91121]
    Other proteins in same PDB: d1lsoa1, d1lsob1
    complexed with nad; mutant

Details for d1lsoa2

PDB Entry: 1lso (more details), 2.6 Å

PDB Description: crystal structure of the s137a mutant of l-3-hydroxyacyl-coa dehydrogenase in complex with nad
PDB Compounds: (A:) 3-hydroxyacyl-CoA dehydrogenase

SCOPe Domain Sequences for d1lsoa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1lsoa2 c.2.1.6 (A:12-203) Short chain L-3-hydroxyacyl CoA dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1lsoa2:

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Timeline for d1lsoa2:

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