SCOP 1.71: Domain d1j3vb1: 1j3v B:158-289

Lineage for d1j3vb1 (1j3v B:158-289)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
   multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry

4. Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (10 families)
   N-terminal domain is Rossmann-fold with a family-specific C-terminal extension

5. Family a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (2 proteins)
   Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain

6. Protein Hydroxyisobutyrate dehydrogenase [101357] (2 species)
   forms similar dimeric and tetrameric structures to the 6-phosphogluconate dehydrogenase domain and its dimer, respectively

7. Species Thermus thermophilus [TaxId:274] [101358] (1 PDB entry)

8. Domain d1j3vb1: 1j3v B:158-289 [90827]
   Other proteins in same PDB: d1j3va2, d1j3vb2, d1j3vc2, d1j3vd2

Details for d1j3vb1

PDB Entry: 1j3v, 1.8 Å

PDB Description: Structure of Hydroxyisobutyrate Dehydrogenase from Thermus Thermophilus HB8

SCOP Domain Sequences for d1j3vb1:

Sequence; same for both SEQRES and ATOM records:

>d1j3vb1 a.100.1.1 (B:158-289) Hydroxyisobutyrate dehydrogenase {Thermus thermophilus}
vgaghavkainnallavnlwaagegllalvkqgvsaekalevinassgrsnatenlipqr
vltrafpktfalgllvkdlgiamgvldgekapspllrlarevyemakrelgpdadhveal
rllerwggveir

Timeline for d1j3vb1:

• d1j3vb1 first appeared in SCOP 1.67
  
• d1j3vb1 appears in SCOP 1.69
  
• d1j3vb1 does not appear in SCOP 1.73