SCOPe 2.05: Domain d1j0sa_: 1j0s A:

Lineage for d1j0sa_ (1j0s A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.2: Interleukin-1 (IL-1) [50362] (6 proteins)

6. Protein Interleukin-18 [101782] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101783] (4 PDB entries)

8. Domain d1j0sa_: 1j0s A: [90747]

Details for d1j0sa_

PDB Entry: 1j0s

PDB Description: solution structure of the human interleukin-18

PDB Compounds: (A:) Interleukin-18

SCOPe Domain Sequences for d1j0sa_:

Sequence; same for both SEQRES and ATOM records:

>d1j0sa_ b.42.1.2 (A:) Interleukin-18 {Human (Homo sapiens) [TaxId: 9606]}
yfgklesklsvirnlndqvlfidqgnrplfedmtdsdcrdnaprtifiismykdsqprgm
avtisvkcekistlscenkiisfkemnppdnikdtksdiiffqrsvpghdnkmqfesssy
egyflacekerdlfklilkkedelgdrsimftvqned

Timeline for d1j0sa_:

• d1j0sa_ first appeared in SCOP 1.67
  
• d1j0sa_ appears in SCOPe 2.04
  
• d1j0sa_ appears in SCOPe 2.06
  
• d1j0sa_ appears in the current release, SCOPe 2.08