SCOP 1.71: Domain d1j05b_: 1j05 B:

Lineage for d1j05b_ (1j05 B:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (148 PDB entries)

8. Domain d1j05b_: 1j05 B: [90736]
   Other proteins in same PDB: d1j05a_, d1j05l_

Details for d1j05b_

PDB Entry: 1j05, 1.5 Å

PDB Description: The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment

SCOP Domain Sequences for d1j05b_:

Sequence; same for both SEQRES and ATOM records:

>d1j05b_ b.1.1.1 (B:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2}
evqlqqsgaelvepgasvklsctasgfnikdtymhwvkqrpeqglewigridpangnsky
vpkfqgkatitadtssntaylqltsltsedtavyycapfgyyvsdyamaywgqgtsvtvs
s

Timeline for d1j05b_:

• d1j05b_ first appeared in SCOP 1.67
  
• d1j05b_ appears in SCOP 1.69
  
• d1j05b_ appears in SCOP 1.73
  
• d1j05b_ appears in the current release, SCOPe 2.08