SCOP 1.71: Domain d1h3cb2: 1h3c B:37-307

Lineage for d1h3cb2 (1h3c B:37-307)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.102: alpha/alpha toroid [48207] (5 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (4 families)

5. Family a.102.4.2: Terpene synthases [48243] (2 proteins)
   consists of two toroid domains: one of six and one of five hairpins

6. Protein Squalene-hopene cyclase [48244] (1 species)

7. Species Alicyclobacillus acidocaldarius [TaxId:405212] [48245] (16 PDB entries)

8. Domain d1h3cb2: 1h3c B:37-307 [90589]

Details for d1h3cb2

PDB Entry: 1h3c, 2.9 Å

PDB Description: structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme

SCOP Domain Sequences for d1h3cb2:

Sequence; same for both SEQRES and ATOM records:

>d1h3cb2 a.102.4.2 (B:37-307) Squalene-hopene cyclase {Alicyclobacillus acidocaldarius}
lsnvtmeaeyvllchildrvdrdrmekirryllheqredgtwalypggppdldttieayv
alkyigmsrdeepmqkalrfiqsqggiessrvftrmwlalvgeypwekvpmvppeimflg
krmplniyefgswaratvvalsivmsrqpvfplperarvpelyetdvpprrrgakggggw
ifdaldralhgyqklsvhpfrraaeiraldwllerqagdgswggiqppwfyalialkild
mtqhpafikgweglelygveldyggwmfqas

Timeline for d1h3cb2:

• d1h3cb2 first appeared in SCOP 1.67
  
• d1h3cb2 appears in SCOP 1.69
  
• d1h3cb2 appears in SCOP 1.73
  
• d1h3cb2 appears in the current release, SCOPe 2.08