Lineage for Species: Human (Homo sapiens), type I [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2943253Fold d.37: CBS-domain pair [54630] (1 superfamily)
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. 2943254Superfamily d.37.1: CBS-domain pair [54631] (2 families) (S)
  5. 2943255Family d.37.1.1: CBS-domain pair [54632] (21 proteins)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain
  6. 2943353Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
  7. 2943356Species Human (Homo sapiens), type I [TaxId:9606] [89899] (1 PDB entry)

PDB entry in Species: Human (Homo sapiens), type I [TaxId: 9606]:

  • Domain(s) for 1jcn:
    1. 2943357Domain d1jcna4: 1jcn A:112-231 [144356]
      Other proteins in same PDB: d1jcna1, d1jcnb1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with cpr

      fragment; missing more than one-third of the common structure and/or sequence
    2. 2943358Domain d1jcnb4: 1jcn B:112-231 [144357]
      Other proteins in same PDB: d1jcna1, d1jcnb1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with cpr

      fragment; missing more than one-third of the common structure and/or sequence

More info for Species Human (Homo sapiens), type I [TaxId:9606] from d.37.1.1 Type II inosine monophosphate dehydrogenase CBS domains

Timeline for Species Human (Homo sapiens), type I [TaxId:9606] from d.37.1.1 Type II inosine monophosphate dehydrogenase CBS domains: