Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1394913Fold c.111: Activating enzymes of the ubiquitin-like proteins [69571] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 32145678; strands 6 and 8 are antiparallel to the rest
  4. 1394914Superfamily c.111.1: Activating enzymes of the ubiquitin-like proteins [69572] (3 families) (S)
    transfer adenylyl group to the C-terminal carboxyl group of the ubiquitin and MoaD/ThiS-related proteins
    the ATP nucleotide-binding site is similar to that of the NAD-binding Rossmann-folds
  5. 1394921Family c.111.1.2: Ubiquitin activating enzymes (UBA) [89763] (2 proteins)
    the common fold is elaborated with additional (sub)domains
  6. 1394922Protein Amyloid beta precursor protein-binding protein 1, APPBP1 [89766] (1 species)
    a subunit of the heterodimeric E1 enzyme for NEDD8; contains a large insertion (residues 170-487) that can be divided into 3 units similar to the UBA3 insertion
  7. 1394923Species Human (Homo sapiens) [TaxId:9606] [89767] (8 PDB entries)
    Uniprot Q13564

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1r4m:
    1. 1394937Domain d1r4ma_: 1r4m A: [96999]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
    2. 1394938Domain d1r4mc_: 1r4m C: [97001]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
    3. 1394939Domain d1r4me_: 1r4m E: [97003]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
    4. 1394940Domain d1r4mg_: 1r4m G: [97005]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
  2. Domain(s) for 1r4n:
    1. 1394945Domain d1r4na_: 1r4n A: [97011]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
    2. 1394946Domain d1r4nc_: 1r4n C: [97013]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
    3. 1394947Domain d1r4ne_: 1r4n E: [97015]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
    4. 1394948Domain d1r4ng_: 1r4n G: [97017]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
  3. Domain(s) for 1tt5:
    1. 1394926Domain d1tt5a_: 1tt5 A: [107291]
      Other proteins in same PDB: d1tt5b_, d1tt5d_
      complexed with zn
    2. 1394927Domain d1tt5c_: 1tt5 C: [107293]
      Other proteins in same PDB: d1tt5b_, d1tt5d_
      complexed with zn
  4. Domain(s) for 1yov:
    1. 1394924Domain d1yova_: 1yov A: [123785]
      Other proteins in same PDB: d1yovb_, d1yovd_
      automated match to d1tt5a_
      complexed with zn
    2. 1394925Domain d1yovc_: 1yov C: [123787]
      Other proteins in same PDB: d1yovb_, d1yovd_
      automated match to d1tt5a_
      complexed with zn
  5. Domain(s) for 2nvu:
  6. Domain(s) for 3dbh:
    1. 1394928Domain d3dbha_: 3dbh A: [157468]
      Other proteins in same PDB: d3dbhb_, d3dbhd_, d3dbhf_, d3dbhh_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
    2. 1394929Domain d3dbhc_: 3dbh C: [157469]
      Other proteins in same PDB: d3dbhb_, d3dbhd_, d3dbhf_, d3dbhh_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
    3. 1394930Domain d3dbhe_: 3dbh E: [157470]
      Other proteins in same PDB: d3dbhb_, d3dbhd_, d3dbhf_, d3dbhh_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
    4. 1394931Domain d3dbhg_: 3dbh G: [157471]
      Other proteins in same PDB: d3dbhb_, d3dbhd_, d3dbhf_, d3dbhh_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
  7. Domain(s) for 3dbl:
    1. 1394932Domain d3dbla_: 3dbl A: [157473]
      Other proteins in same PDB: d3dblb_, d3dbld_, d3dblf_, d3dblh_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
    2. 1394933Domain d3dblc_: 3dbl C: [157475]
      Other proteins in same PDB: d3dblb_, d3dbld_, d3dblf_, d3dblh_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
    3. 1394934Domain d3dble_: 3dbl E: [157477]
      Other proteins in same PDB: d3dblb_, d3dbld_, d3dblf_, d3dblh_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
    4. 1394935Domain d3dblg_: 3dbl G: [157479]
      Other proteins in same PDB: d3dblb_, d3dbld_, d3dblf_, d3dblh_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
  8. Domain(s) for 3dbr:
    1. 1394941Domain d3dbra1: 3dbr A:6-534 [157482]
      automatically matched to d1tt5a_
      complexed with zn
    2. 1394942Domain d3dbrc1: 3dbr C:6-534 [157483]
      automatically matched to d1tt5a_
      complexed with zn
    3. 1394943Domain d3dbre1: 3dbr E:6-534 [157484]
      automatically matched to d1tt5a_
      complexed with zn
    4. 1394944Domain d3dbrg1: 3dbr G:6-534 [157485]
      automatically matched to d1tt5a_
      complexed with zn

More info for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 Amyloid beta precursor protein-binding protein 1, APPBP1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 Amyloid beta precursor protein-binding protein 1, APPBP1: