Lineage for Protein: An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129933Family c.66.1.25: mRNA cap methylase [88785] (3 protein domains)
  6. 2129934Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 [89741] (2 species)
    structurally and functionally similar to VP39

Species:

  1. 2129935Flavivirus (Dengue virus type 2) [TaxId:12637] [89742] (8 PDB entries)
    Uniprot P12823 2495-2756
    1. Domain for 1l9k:
    2. Domain for 1r6a:
    3. Domain for 2p1d:
    4. Domain for 2p3l:
    5. Domain for 2p3o:
    6. Domain for 2p3q:
    7. Domain for 2p40:
    8. Domain for 2p41:
  2. 2129944Murray valley encephalitis virus (strain mve-1-51) [TaxId:301478] [187362] (6 PDB entries)
    1. Domains for 2px2:
      1. 2129946Domain d2px2a_: 2px2 A: [167319]
        automated match to d1r6aa_
        complexed with cl, sah
      2. 2129947Domain d2px2b_: 2px2 B: [167320]
        automated match to d1r6aa_
        complexed with cl, sah
    2. Domain for 2px4:
    3. Domains for 2px5:
      1. 2129950Domain d2px5a_: 2px5 A: [167322]
        automated match to d1r6aa_
        complexed with sah, so4
      2. 2129951Domain d2px5b_: 2px5 B: [167323]
        automated match to d1r6aa_
        complexed with sah, so4
    4. Domains for 2px8:
      1. 2129948Domain d2px8a_: 2px8 A: [167324]
        automated match to d1r6aa_
        complexed with 3po, cl, gol, mgt, sah
      2. 2129949Domain d2px8b_: 2px8 B: [167325]
        automated match to d1r6aa_
        complexed with 3po, cl, gol, mgt, sah
    5. Domains for 2pxa:
      1. 2129952Domain d2pxaa_: 2pxa A: [167326]
        automated match to d1r6aa_
        complexed with gtp, sah
      2. 2129953Domain d2pxab_: 2pxa B: [167327]
        automated match to d1r6aa_
        complexed with gtp, sah
    6. Domain for 2pxc:

More info for Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase

Timeline for Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase:

  • Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase first appeared in SCOP 1.65
  • Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase appears in SCOPe 2.05