SCOPe 2.08: Protein: An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5

Lineage for Protein: An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)
Family c.66.1.25: mRNA cap methylase [88785] (4 proteins)
Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 [89741] (2 species)
structurally and functionally similar to VP39

Species:

Flavivirus (Dengue virus type 2) [TaxId:12637] [89742] (8 PDB entries)
Uniprot P12823 2495-2756
1. Domain for 1l9k:
  - Domain d1l9ka_: 1l9k A: [84569]
    complexed with sah, so4
2. Domain for 1r6a:
  - Domain d1r6aa_: 1r6a A: [104817]
    complexed with rvp, sah, so4
3. Domain for 2p1d:
  - Domain d2p1da_: 2p1d A: [139456]
    automated match to d1l9ka_
    complexed with 5gp, sah, so4
4. Domain for 2p3l:
  - Domain d2p3la_: 2p3l A: [149180]
    automated match to d1l9ka_
    complexed with cit, g3a, gol, sah, so4
5. Domain for 2p3o:
  - Domain d2p3oa_: 2p3o A: [149182]
    automated match to d1l9ka_
    complexed with cit, gta, sah, so4
6. Domain for 2p3q:
  - Domain d2p3qa_: 2p3q A: [149185]
    automated match to d1l9ka_
    complexed with gp3, sah, so4
7. Domain for 2p40:
  - Domain d2p40a_: 2p40 A: [149192]
    automated match to d1l9ka_
    complexed with gtg, so4
8. Domain for 2p41:
  - Domain d2p41a_: 2p41 A: [149193]
    automated match to d1l9ka_
    complexed with cit, g1g, gol, sah, so4
Murray valley encephalitis virus (strain mve-1-51) [TaxId:301478] [187362] (6 PDB entries)
1. Domains for 2px2:
  1. Domain d2px2a_: 2px2 A: [167319]
    automated match to d1r6aa_
    complexed with cl, sah
  2. Domain d2px2b_: 2px2 B: [167320]
    automated match to d1r6aa_
    complexed with cl, sah
2. Domain for 2px4:
  - Domain d2px4a_: 2px4 A: [167321]
    automated match to d1r6aa_
    complexed with cl, gol, sah, so4, unx
3. Domains for 2px5:
  1. Domain d2px5a_: 2px5 A: [167322]
    automated match to d1r6aa_
    complexed with sah, so4
  2. Domain d2px5b_: 2px5 B: [167323]
    automated match to d1r6aa_
    complexed with sah, so4
4. Domains for 2px8:
  1. Domain d2px8a_: 2px8 A: [167324]
    automated match to d1r6aa_
    complexed with 3po, cl, gol, mgt, sah
  2. Domain d2px8b_: 2px8 B: [167325]
    automated match to d1r6aa_
    complexed with 3po, cl, gol, mgt, sah
5. Domains for 2pxa:
  1. Domain d2pxaa_: 2pxa A: [167326]
    automated match to d1r6aa_
    complexed with gtp, sah
  2. Domain d2pxab_: 2pxa B: [167327]
    automated match to d1r6aa_
    complexed with gtp, sah
6. Domain for 2pxc:
  - Domain d2pxca_: 2pxc A: [167328]
    automated match to d1r6aa_
    complexed with g3a, sam

More info for Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase

Timeline for Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase:

Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase first appeared in SCOP 1.65
Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 from c.66.1.25: mRNA cap methylase appears in SCOPe 2.07