Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.10: TK-like PP module [88760] (3 proteins) different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain |
Protein Transketolase (TK), PP module [88761] (4 species) |
Species Escherichia coli [TaxId:562] [89656] (4 PDB entries) |
Domain d1qgda2: 1qgd A:2-332 [88368] Other proteins in same PDB: d1qgda1, d1qgda3, d1qgdb1, d1qgdb3 complexed with ca, so4, tpp |
Domain d1qgdb2: 1qgd B:2-332 [88371] Other proteins in same PDB: d1qgda1, d1qgda3, d1qgdb1, d1qgdb3 complexed with ca, so4, tpp |
Domain d2r5na2: 2r5n A:2-332 [151592] Other proteins in same PDB: d2r5na1, d2r5na3, d2r5nb1, d2r5nb3 automated match to d1qgda2 complexed with ca, edo, r5p, rp5, tpp |
Domain d2r5nb2: 2r5n B:2-332 [151595] Other proteins in same PDB: d2r5na1, d2r5na3, d2r5nb1, d2r5nb3 automated match to d1qgda2 complexed with ca, edo, r5p, rp5, tpp |
Domain d2r8oa2: 2r8o A:2-332 [151732] Other proteins in same PDB: d2r8oa1, d2r8oa3, d2r8ob1, d2r8ob3 automated match to d1qgda2 complexed with ca, edo, t5x |
Domain d2r8ob2: 2r8o B:2-332 [151735] Other proteins in same PDB: d2r8oa1, d2r8oa3, d2r8ob1, d2r8ob3 automated match to d1qgda2 complexed with ca, edo, t5x |
Domain d2r8pa2: 2r8p A:2-332 [151738] Other proteins in same PDB: d2r8pa1, d2r8pa3, d2r8pb1, d2r8pb3 automated match to d1qgda2 complexed with ca, edo, t6f |
Domain d2r8pb2: 2r8p B:2-332 [151741] Other proteins in same PDB: d2r8pa1, d2r8pa3, d2r8pb1, d2r8pb3 automated match to d1qgda2 complexed with ca, edo, t6f |
Timeline for Species Escherichia coli [TaxId:562] from c.36.1.10 Transketolase (TK), PP module: