Lineage for Species: Escherichia coli [TaxId: 562]

  1. Root: SCOPe 2.04
  2. 1565955Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1592643Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 1592644Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. Family c.36.1.6: TK-like Pyr module [88735] (2 proteins)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. Protein Transketolase (TK), Pyr module [88736] (4 species)
  7. Species Escherichia coli [TaxId:562] [89650] (1 PDB entry)

PDB entry in Species: Escherichia coli [TaxId: 562]:

More info for Species Escherichia coli [TaxId:562] from c.36.1.6 Transketolase (TK), Pyr module

Timeline for Species Escherichia coli [TaxId:562] from c.36.1.6 Transketolase (TK), Pyr module: