SCOP 1.69: Protein: tRNA(m1G37)-methyltransferase TrmD

Root: SCOP 1.69
Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
Fold c.116: alpha/beta knot [75216] (1 superfamily)
core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot
Superfamily c.116.1: alpha/beta knot [75217] (5 families)
known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
all known members have dimeric structures
Family c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (1 protein)
fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain
Protein tRNA(m1G37)-methyltransferase TrmD [89630] (3 species)

Aquifex aeolicus [TaxId:63363] [102278] (1 PDB entry)
- Domains for 1oy5:
  1. Domain d1oy5a_: 1oy5 A: [93718]
  2. Domain d1oy5b_: 1oy5 B: [93719]
  3. Domain d1oy5c_: 1oy5 C: [93720]
    a TrmD topoisomer that lacks the knot; misfolded inactive structure?
Escherichia coli [TaxId:562] [110499] (1 PDB entry)
- Domain for 1p9p:
  - Domain d1p9pa_: 1p9p A: [104092]
Haemophilus influenzae [TaxId:727] [89631] (4 PDB entries)
1. Domain for 1uaj:
  - Domain d1uaja_: 1uaj A: [88381]
2. Domain for 1uak:
  - Domain d1uaka_: 1uak A: [88382]
3. Domain for 1ual:
  - Domain d1uala_: 1ual A: [88383]
4. Domain for 1uam:
  - Domain d1uama_: 1uam A: [88384]

Timeline for Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD:

Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD first appeared in SCOP 1.65
Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD appears in SCOP 1.67
Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD appears in SCOP 1.71
Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD appears in the current release, SCOPe 2.08