SCOPe 2.01: Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain

Lineage for Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.14: ClpP/crotonase [52095] (1 superfamily)
   core: 4 turns of (beta-beta-alpha)n superhelix

4. Superfamily c.14.1: ClpP/crotonase [52096] (5 families)

5. Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain [89572] (6 proteins)
   Pfam PF01039
   the active site is formed by two different homologous subunits or domains of this fold

Proteins:

1. Acetyl-coenzyme A carboxylase [89573] (1 species)
   duplication: consists of two similar structural domains forming a functional domain of a larger multifunctional enzyme

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89574] (7 PDB entries)
     Uniprot Q00955 1482-2196

2. Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, AccA [142012] (1 species)

   • Species Escherichia coli [TaxId:562] [142013] (1 PDB entry)
     Uniprot P0ABD5 4-319

3. Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, AccD [142014] (1 species)

   • Species Escherichia coli [TaxId:562] [142015] (1 PDB entry)
     Uniprot P0A9Q6 23-285

4. Glutaconyl-CoA decarboxylase A subunit [102210] (1 species)

   • Species Acidaminococcus fermentans [TaxId:905] [102211] (1 PDB entry)

5. Methylmalonyl-CoA carboxyltransferase (transcarboxylase 12S) [89575] (1 species)

   • Species Propionibacterium freudenreichii [TaxId:1744] [89576] (2 PDB entries)

6. Propionyl-CoA carboxylase complex B subunit, PccB [117466] (3 species)

   1. Species Mycobacterium tuberculosis [TaxId:1773] [142010] (1 PDB entry)
      Uniprot P96885 20-277! Uniprot P96885 278-548

   2. Species Streptomyces coelicolor [TaxId:1902] [117467] (4 PDB entries)
      Uniprot Q9X4K7

   3. Species Thermotoga maritima [TaxId:2336] [142011] (1 PDB entry)
      Uniprot Q9WZH5 1-251! Uniprot Q9WZH5 252-515

More info for Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain

Timeline for Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain:

• Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain first appeared in SCOP 1.65
  
• Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain appears in SCOP 1.75
  
• Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain appears in SCOPe 2.02
  
• Family c.14.1.4: Biotin dependent carboxylase carboxyltransferase domain appears in the current release, SCOPe 2.08