SCOPe 2.07: Family c.8.7.1: RraA-like

Lineage for Family c.8.7.1: RraA-like

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.8: The "swivelling" beta/beta/alpha domain [52008] (10 superfamilies)
   3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
   this domain is thought to be mobile in most multi-domain proteins known to contain it

4. Superfamily c.8.7: RraA-like [89562] (2 families)
   structural similarity and possible distant homology to the phosphohistidine domain of pyruvate phosphate dikinase

5. Family c.8.7.1: RraA-like [89563] (5 proteins)
   aka MenG-like; characterized as regulator of RNase E activity A (RraA) that globally modulates RNA abundance in E. coli
   automatically mapped to Pfam PF03737

Proteins:

1. Demethylmenaquinone methyltransferase [102196] (1 species)
   as (mis)annotated in the PDB entry; RraA homologue

   • Species Thermus thermophilus [TaxId:274] [102197] (1 PDB entry)

2. Hypothetical protein Rv3853 [89564] (1 species)
   RraA homologue; (mis)annotated as a probable MenG-like demethylmenaquinone methyltransferase

   • Species Mycobacterium tuberculosis [TaxId:1773] [89565] (1 PDB entry)

3. Hypothetical protein VC2366 [102194] (1 species)
   RraA homologue

   • Species Vibrio cholerae [TaxId:666] [102195] (1 PDB entry)

4. Regulator of RNase E activity RraA (MenG) [102192] (1 species)

   • Species Escherichia coli [TaxId:562] [102193] (1 PDB entry)

5. automated matches [195200] (1 species)
   not a true protein

   • Species Escherichia coli K-12 [TaxId:83333] [195201] (1 PDB entry)

More info for Family c.8.7.1: RraA-like

Timeline for Family c.8.7.1: RraA-like:

• Family c.8.7.1: RraA-like first appeared in SCOP 1.65
  
• Family c.8.7.1: RraA-like appears in SCOPe 2.06
  
• Family c.8.7.1: RraA-like appears in the current release, SCOPe 2.08