Lineage for Protein: Shikimate 5-dehydrogenase AroE

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2429805Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 protein domains)
    extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site
  6. 2430049Protein Shikimate 5-dehydrogenase AroE [89538] (6 species)

Species:

  1. 2430050Aquifex aeolicus [TaxId:63363] [225281] (3 PDB entries)
    1. Domains for 2hk7:
      1. 2430059Domain d2hk7a2: 2hk7 A:106-269 [204591]
        Other proteins in same PDB: d2hk7a1, d2hk7b1
        automated match to d1nvta1
        complexed with hg
      2. 2430060Domain d2hk7b2: 2hk7 B:106-268 [204593]
        Other proteins in same PDB: d2hk7a1, d2hk7b1
        automated match to d1nvta1
        complexed with hg
    2. Domains for 2hk8:
      1. 2430051Domain d2hk8a2: 2hk8 A:106-266 [204595]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
      2. 2430052Domain d2hk8b2: 2hk8 B:106-266 [204597]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
      3. 2430053Domain d2hk8c2: 2hk8 C:106-265 [204599]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
      4. 2430054Domain d2hk8d2: 2hk8 D:106-266 [204601]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
      5. 2430055Domain d2hk8e2: 2hk8 E:106-266 [204603]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
      6. 2430056Domain d2hk8f2: 2hk8 F:106-264 [204605]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
      7. 2430057Domain d2hk8g2: 2hk8 G:106-266 [204607]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
      8. 2430058Domain d2hk8h2: 2hk8 H:106-266 [204609]
        Other proteins in same PDB: d2hk8a1, d2hk8b1, d2hk8c1, d2hk8d1, d2hk8e1, d2hk8f1, d2hk8g1, d2hk8h1
        automated match to d1nvta1
    3. Domains for 2hk9:
      1. 2430061Domain d2hk9a2: 2hk9 A:106-269 [204611]
        Other proteins in same PDB: d2hk9a1, d2hk9b1, d2hk9c1, d2hk9d1
        automated match to d1nvta1
        complexed with atr, nap, skm
      2. 2430062Domain d2hk9b2: 2hk9 B:106-267 [204613]
        Other proteins in same PDB: d2hk9a1, d2hk9b1, d2hk9c1, d2hk9d1
        automated match to d1nvta1
        complexed with atr, nap, skm
      3. 2430063Domain d2hk9c2: 2hk9 C:106-266 [204615]
        Other proteins in same PDB: d2hk9a1, d2hk9b1, d2hk9c1, d2hk9d1
        automated match to d1nvta1
        complexed with atr, nap, skm
      4. 2430064Domain d2hk9d2: 2hk9 D:106-266 [204617]
        Other proteins in same PDB: d2hk9a1, d2hk9b1, d2hk9c1, d2hk9d1
        automated match to d1nvta1
        complexed with atr, nap, skm
  2. 2430065Escherichia coli [TaxId:562] [89539] (1 PDB entry)
  3. 2430070Geobacillus kaustophilus [TaxId:1462] [225426] (1 PDB entry)
  4. 2430073Haemophilus influenzae [TaxId:727] [102173] (2 PDB entries)
    1. Domains for 1p74:
      1. 2430075Domain d1p74a1: 1p74 A:102-272 [94206]
        Other proteins in same PDB: d1p74a2, d1p74b2
      2. 2430076Domain d1p74b1: 1p74 B:102-272 [94208]
        Other proteins in same PDB: d1p74a2, d1p74b2
    2. Domain for 1p77:
  5. 2430077Methanococcus jannaschii [TaxId:2190] [89540] (1 PDB entry)
    MJ1084
  6. 2430080Staphylococcus epidermidis [TaxId:176279] [225658] (2 PDB entries)
    1. Domain for 3don:
    2. Domain for 3doo:

More info for Protein Shikimate 5-dehydrogenase AroE from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain

Timeline for Protein Shikimate 5-dehydrogenase AroE from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain:

  • Protein Shikimate 5-dehydrogenase AroE from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain first appeared in SCOP 1.65
  • Protein Shikimate 5-dehydrogenase AroE from c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain appears in SCOPe 2.06