SCOPe 2.04: Superfamily b.129.1: AbrB/MazE/MraZ-like

Lineage for Superfamily b.129.1: AbrB/MazE/MraZ-like

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.129: Double-split beta-barrel [89446] (2 superfamilies)
   pseudobarrel; capped on both ends by alpha-helices

4. Superfamily b.129.1: AbrB/MazE/MraZ-like [89447] (3 families)
   members of this superfamily are known or predicted to have DNA-binding function

Families:

1. b.129.1.1: Kis/PemI addiction antidote [89448] (1 protein)
   forms intertwined homodimer

2. b.129.1.2: Hypothetical protein MraZ [102020] (1 protein)
   duplication: contains two interlocking repeats of similar sequence arranged as subunits in the MazE homodimer

3. b.129.1.3: AbrB N-terminal domain-like [54743] (2 proteins)
   dimeric fold similar to MazE; the DNA-binding site is similar to the conserved surface site of MraZ
   automatically mapped to Pfam PF04014

More info for Superfamily b.129.1: AbrB/MazE/MraZ-like

Timeline for Superfamily b.129.1: AbrB/MazE/MraZ-like:

• Superfamily b.129.1: AbrB/MazE/MraZ-like first appeared in SCOP 1.65, called Superfamily b.129.1: Kis/PemI addiction antidote
  
• Superfamily b.129.1: AbrB/MazE/MraZ-like appears in SCOPe 2.03
  
• Superfamily b.129.1: AbrB/MazE/MraZ-like appears in SCOPe 2.05
  
• Superfamily b.129.1: AbrB/MazE/MraZ-like appears in the current release, SCOPe 2.08