SCOPe 2.05: Fold b.129: Double-split beta-barrel

Lineage for Fold b.129: Double-split beta-barrel

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.129: Double-split beta-barrel [89446] (2 superfamilies)
   pseudobarrel; capped on both ends by alpha-helices

Superfamilies:

1. b.129.1: AbrB/MazE/MraZ-like [89447] (3 families)
   members of this superfamily are known or predicted to have DNA-binding function

2. b.129.2: AF2212/PG0164-like [141694] (2 families)
   six-stranded barrel, topologically similar to the Reductase/isomerase/elongation factor domain fold (50412)

More info for Fold b.129: Double-split beta-barrel

Timeline for Fold b.129: Double-split beta-barrel:

• Fold b.129: Double-split beta-barrel first appeared in SCOP 1.65, called Fold b.129: Kis/PemI addiction antidote
  
• Fold b.129: Double-split beta-barrel appears in SCOPe 2.04
  
• Fold b.129: Double-split beta-barrel appears in SCOPe 2.06
  
• Fold b.129: Double-split beta-barrel appears in the current release, SCOPe 2.08