SCOPe 2.08: Family a.183.1.1: Nop domain

Lineage for Family a.183.1.1: Nop domain

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.183: Nop domain [89123] (1 superfamily)
   multihelical; array of longer and shorter helices; contains an alpha-hairpin dimerisation subdomain

4. Superfamily a.183.1: Nop domain [89124] (2 families)

5. Family a.183.1.1: Nop domain [89125] (2 proteins)
   putative snoRNA binding domain

Proteins:

1. Nop5p [89126] (1 species)
   also contains an N-terminal, fibrillarin-binding alpha+beta subdomain

   • Species Archaeoglobus fulgidus [TaxId:2234] [89127] (1 PDB entry)
     AF2088

2. U4/U6 small nuclear ribonucleoprotein Prp31 [158762] (2 species)
   contains insertion of a small 4-helical bundle at the tip of a long alpha-hairpin arm; this insertion approximately corresponds to the NOSIC (NUC001) domain; Pfam PF08060

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [346215] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [158763] (2 PDB entries)
      Uniprot Q8WWY3 85-333

More info for Family a.183.1.1: Nop domain

Timeline for Family a.183.1.1: Nop domain:

• Family a.183.1.1: Nop domain first appeared in SCOP 1.65
  
• Family a.183.1.1: Nop domain appears in SCOPe 2.07