Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991814Protein Interleukin-22 (IL-22) [89036] (1 species)
  7. 1991815Species Human (Homo sapiens) [TaxId:9606] [89037] (5 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1m4r:
    1. 1991817Domain d1m4ra_: 1m4r A: [84799]
    2. 1991818Domain d1m4rb_: 1m4r B: [84800]
  2. Domain(s) for 1ykb:
    1. 1991820Domain d1ykba_: 1ykb A: [123503]
      automated match to d1m4ra_
      complexed with nag
    2. 1991821Domain d1ykbb_: 1ykb B: [123504]
      automated match to d1m4ra_
      complexed with nag
    3. 1991822Domain d1ykbc_: 1ykb C: [123505]
      automated match to d1m4ra_
      complexed with nag
    4. 1991823Domain d1ykbd_: 1ykb D: [123506]
      automated match to d1m4ra_
      complexed with nag
    5. 1991824Domain d1ykbe_: 1ykb E: [123507]
      automated match to d1m4ra_
      complexed with nag
    6. 1991825Domain d1ykbf_: 1ykb F: [123508]
      automated match to d1m4ra_
      complexed with nag
  3. Domain(s) for 3dlq:
  4. Domain(s) for 3g9v:
    1. 1991826Domain d3g9vb_: 3g9v B: [176455]
      automated match to d1m4ra_
    2. 1991827Domain d3g9vd_: 3g9v D: [176456]
      automated match to d1m4ra_
  5. Domain(s) for 3q1s:

More info for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interleukin-22 (IL-22)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interleukin-22 (IL-22):