Lineage for Species: Malaria parasite (Plasmodium falciparum) [TaxId: 5833]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2136822Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2136823Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain [53610] (2 species)
  7. 2136840Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [88963] (5 PDB entries)

PDB entries in Species: Malaria parasite (Plasmodium falciparum) [TaxId: 5833]:

  1. Domain(s) for 1j3i:
    1. 2136843Domain d1j3ia_: 1j3i A: [84062]
      Other proteins in same PDB: d1j3ic_, d1j3id_
      complexed with ndp, ump, wra
    2. 2136844Domain d1j3ib_: 1j3i B: [84063]
      Other proteins in same PDB: d1j3ic_, d1j3id_
      complexed with ndp, ump, wra
  2. Domain(s) for 1j3j:
    1. 2136845Domain d1j3ja_: 1j3j A: [84066]
      Other proteins in same PDB: d1j3jc_, d1j3jd_
      complexed with cp6, ndp, ump; mutant
    2. 2136846Domain d1j3jb_: 1j3j B: [84067]
      Other proteins in same PDB: d1j3jc_, d1j3jd_
      complexed with cp6, ndp, ump; mutant
  3. Domain(s) for 1j3k:
    1. 2136841Domain d1j3ka_: 1j3k A: [84070]
      Other proteins in same PDB: d1j3kc_, d1j3kd_
      complexed with ndp, ump, wra; mutant
    2. 2136842Domain d1j3kb_: 1j3k B: [84071]
      Other proteins in same PDB: d1j3kc_, d1j3kd_
      complexed with ndp, ump, wra; mutant
  4. Domain(s) for 3dg8:
    1. 2136847Domain d3dg8a_: 3dg8 A: [199230]
      Other proteins in same PDB: d3dg8c_, d3dg8d_
      automated match to d1j3ka_
      complexed with ndp, rj6, ump; mutant
    2. 2136848Domain d3dg8b_: 3dg8 B: [199231]
      Other proteins in same PDB: d3dg8c_, d3dg8d_
      automated match to d1j3kb_
      complexed with ndp, rj6, ump; mutant
  5. Domain(s) for 3dga:
    1. 2136849Domain d3dgaa_: 3dga A: [199232]
      Other proteins in same PDB: d3dgac_, d3dgad_
      automated match to d1j3ia_
      complexed with ndp, rj1, ump
    2. 2136850Domain d3dgab_: 3dga B: [199233]
      Other proteins in same PDB: d3dgac_, d3dgad_
      automated match to d1j3ia_
      complexed with ndp, rj1, ump

More info for Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] from c.71.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain

Timeline for Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] from c.71.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain: