Lineage for Family c.66.1.25: mRNA cap methylase

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2892669Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2892670Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families) (S)
  5. 2893582Family c.66.1.25: mRNA cap methylase [88785] (4 proteins)

Proteins:

  1. 2893583An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 [89741] (2 species)
    structurally and functionally similar to VP39
    1. 2893584Species Flavivirus (Dengue virus type 2) [TaxId:12637] [89742] (8 PDB entries)
      Uniprot P12823 2495-2756
    2. 2893593Species Murray valley encephalitis virus (strain mve-1-51) [TaxId:301478] [187362] (6 PDB entries)
  2. 2893604Polymerase regulatory subunit VP39 [53361] (2 species)
    1. 2893605Species Vaccinia virus wr [TaxId:10254] [224905] (2 PDB entries)
    2. 2893609Species Vaccinia virus [TaxId:10245] [53362] (17 PDB entries)
  3. 2893627SARS coronavirus nsp16 [419230] (1 species)
    Pfam PF06460
  4. 2893632automated matches [190302] (11 species)
    not a true protein
    1. 2893633Species Dengue virus 2 16681-pdk53 [TaxId:31635] [188733] (1 PDB entry)
    2. 2893635Species Dengue virus 3 [TaxId:11069] [189561] (3 PDB entries)
    3. 2893642Species Dengue virus [TaxId:12637] [189508] (1 PDB entry)
    4. 2893647Species Human betacoronavirus 2c EMC/2012 [TaxId:1235996] [419989] (12 PDB entries)
    5. 2893660Species Human coronavirus oc43 [TaxId:31631] [420140] (1 PDB entry)
    6. 2893662Species SARS coronavirus [TaxId:227859] [419868] (1 PDB entry)
    7. 2893664Species Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049] [420071] (19 PDB entries)
    8. 2893687Species Vaccinia virus [TaxId:10245] [187111] (2 PDB entries)
    9. 2893690Species West Nile virus [TaxId:11082] [187969] (2 PDB entries)
    10. 2893695Species Zika virus (strain mr 766) [TaxId:64320] [322798] (8 PDB entries)
    11. 2893719Species Zika virus [TaxId:64320] [322811] (3 PDB entries)

More info for Family c.66.1.25: mRNA cap methylase

Timeline for Family c.66.1.25: mRNA cap methylase: