Lineage for Family c.66.1.25: mRNA cap methylase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129933Family c.66.1.25: mRNA cap methylase [88785] (3 protein domains)

Protein Domains:

  1. 2129934An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 [89741] (2 species)
    structurally and functionally similar to VP39
    1. 2129935Species Flavivirus (Dengue virus type 2) [TaxId:12637] [89742] (8 PDB entries)
      Uniprot P12823 2495-2756
    2. 2129944Species Murray valley encephalitis virus (strain mve-1-51) [TaxId:301478] [187362] (6 PDB entries)
  2. 2129955Polymerase regulatory subunit VP39 [53361] (2 species)
    1. 2129956Species Vaccinia virus wr [TaxId:10254] [224905] (2 PDB entries)
    2. 2129960Species Vaccinia virus [TaxId:10245] [53362] (17 PDB entries)
  3. 2129978automated matches [190302] (8 species)
    not a true protein
    1. 2129979Species Dengue virus 2 16681-pdk53 [TaxId:31635] [188733] (1 PDB entry)
    2. 2129981Species Dengue virus 3 [TaxId:11069] [189561] (2 PDB entries)
    3. 2129986Species Dengue virus [TaxId:12637] [189508] (1 PDB entry)
    4. 2129991Species Vaccinia virus [TaxId:10245] [187111] (2 PDB entries)
    5. 2129994Species West Nile virus [TaxId:11082] [187969] (2 PDB entries)
    6. 2279497Species Zika virus (strain mr 766) [TaxId:64320] [322798] (7 PDB entries)
    7. 2279510Species Zika virus [TaxId:64320] [322811] (2 PDB entries)
    8. 2281147Species Dengue virus type 3 (strain philippines/h87/1956) [TaxId:408870] [324448] (1 PDB entry)

More info for Family c.66.1.25: mRNA cap methylase

Timeline for Family c.66.1.25: mRNA cap methylase: